书目

AppliedNMRSpectroscopyforChemistsandLifeScientists

内容简介

UnliketraditionalNMRtextbooksforchemists,thisfreshlookatthetopiccombinestheory,technologyandapplicationinawiderangeoffields,targetingbiochemists,medicinalchemists,andstructuralbiologists,aswellasorganicchemists.Thetexthasbeendevelopedfromaone-semestergraduate-levelcoursetaughtbytheauthorsattheUniversityofZurich,andoffersnumerousintuitiveillustrations,trainingexercisesandplain-languageexplanationsofcomplextheory.Dividedintofourmajorparts,thefirstintroducesthetheory,providingaprofoundunderstandingofwhyexperimentswork,withoutarigorousmathematicaltreatmentofallthephysico-chemicalcomputationsanddeliberatelyshorterthaninmostotherNMRtextbooks.Parttwodiscussescurrentinstrumentationandpracticalaspects,includingsamplepreparation,processingofrawdataandtheuseofdatabases,whilethethirdpartfocusesonthemainapplicationofNMR,withexamplesandtrainingspectratakenfromawiderangeofsyntheticandnaturalcompounds.PartfourintroducesaselectionofmodernNMRapplicationsinchemistry,biochemistry,medicinalchemistryandmolecularbiology,explainingtheprotocolsusedandhowtointerprettheresults.Withitsfocusonpracticalaspectsandapplications,thistextwillproveusefullongafterleavingcollege,byhelpinguserstoselectexperimentalmethodsandinsettingupandrunningtheirownNMRexperiments.

作者简介

OliverZerbeistheheadoftheNMRdepartmentattheUniversityofZurich.HestudiedchemistryandobtainedhisPhDunderthesupervisionofWolfgangvonPhilipsborninZurich.AfteraPostdoctoralstayinthegroupofKurtWuthrichattheETHZurichheconductedhisHabilitationattheInstituteofPharmaceuticalSciencesattheETH.In2003hereturnedtohispresentlocationattheUniversityofZurich.Hismaininterestsareinstructuralbiologyandinthestructureofmembraneproteinsinparticular.OliverZerbeistheauthorofapprox.80scientificpublicationsinpeer-reviewedjournalsandhaseditedonebook,'NMRindrugresearch'.

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