内容简介
Groomingisamongthemostevolutionaryancientandhighlyrepresentedbehavioursinmanyanimalspecies.Itrepresentsasignificantproportionofananimal'stotalactivityandbetween30-50%oftheirwakinghours.Recentresearchhasdemonstratedthatgroomingisregulatedbyspecificbraincircuitsandissensitivetostress,aswellastopharmacologiccompoundsandgeneticmanipulation,makingitidealformodellingaffectivedisordersthatariseasafunctionofstressfulenvironments,suchasstressandpost-traumaticstressdisorder.Overaseriesof12chaptersthatintroduceandexplicatethefieldofgroomingresearchanditssignificanceforthehumanandanimalbrain,thisbookcoversthebreadthofgroominganimalmodelswhilesimultaneouslyprovidingsufficientdepthinintroducingtheconceptsandtranslationalapproachestogroomingresearch.Writtenprimarilyforgraduatesandresearcherswithintheneuroscientificcommunity.
作者简介
AllanV.KalueffisprofessorofneuroscienceintheDepartmentofPhysiologyandBiophysicsatGeorgetownUniversityMedicalSchool.Hepublishesactivelyonmodelsofdrug-druganddrug-receptorinteractions,theoriesofbraindisordersandtheirtherapy,andcomplexinterplaybetweencognitive,motivationalandgeneticbasesofanimalbehavior.CarisaL.BergnerisaresearcherintheDepartmentofPhysiologyandBiophysicsatGeorgetownUniversityMedicalSchool.Herresearchcurrentlyinvolvesmouseandzebrafishmodelsofstressanddepression.JustinL.LaPorteholdsapositionattheNationalInstituteofMentalHealthinBethesda,Maryland,USA.Hisresearchemploysbehavioralpharmacologyandmoleculargeneticsapproachestoelucidatethepathogeneticmechanismsofpsychiatricdisorderssuchasdepression,anxiety,andobsessive-compulsivedisorder,withaspecificfocusontheroleofserotonintransporter.