书目

Escherichia coli: Pathogenesis and Pathotypes大肠杆菌：致病型和发病原理，第2版

内容简介

ThesecondeditionofEscherichiacoliisaunique,comprehensiveanalysisofthebiologyandmolecularmechanismsthatenablethisubiquitousorganismtothrive.LeadinginvestigatorsinthefielddiscussthemolecularbasisofE.colipathogenesisfollowedbychaptersongenomicsandevolution.Detaileddescriptionsofdistinctstrainsrevealthemolecularpathogenesisofeachandthecausesofintestinalandextra-intestinalinfectionsinhumans.Thisworkconcludeswithapresentationofvirulencefactorscommontotwoormorepathotypes.Thebookisagreatresourceforreferencesandup-to-dateknowledgeforanyonewhostudiesE.colipathogenesis,eitherasestablishedinvestigatorsorinvestigatorsnewtothefield.Itisalsoanexcellenttextforthosewhoteachmechanismsofpathogenesistograduatestudentsandmedicalstudentsandwishtohaveasourceofknowledgefromwhichtodeveloplectures.*OffersasinglesourceofinformationofE.colipathogenesiswrittenbyexpertauthors*Presentscomprehensivecoverageonmolecularmechanisms,biology,evolutionandgenomicsandrecentadvances

作者简介

MichaelDonnenberg,MDisaProfessorofMedicineandofMicrobiologyandImmunologyattheUniversityofMaryland.Dr.DonnenbergisagraduateoftheColumbiaUniversityCollegeofPhysiciansandSurgeons.HecompletedresidencyinInternalMedicineatwhatisnowtheBayviewCampusofJohnsHopkinsandfellowshipinInfectiousDiseasesatTufts/NewEnglandMedicalCenter.AfteradditionalpostdoctoralresearchtrainingattheCenterforVaccineDevelopmentattheUniversityofMaryland,Dr.Donnenbergjoinedthefacultyin1990.Dr.Donnenberg'sresearchhasfocusedonthemolecularpathogenesisofinfectionsduetoEscherichiacoliandonthebiogenesisandfunctionofbacterialsurfaceappendagescalledTypeIVPilithatareusedbymanypathogenstoadheretohostcellsurfaces.HisworkhasbeencontinuouslyfundedbytheNationalInstitutesofHealthforovertwentyyearsandhasresultedinthepublicationofoveronehundredoriginalmanuscripts,reviews,andbookchapters.HeisaFellowoftheInfectiousDiseasesSocietyofAmericaandtheAmericanAcademyofMicrobiologyandamemberoftheAmericanSocietyforClinicalInvestigation.HeisarecipientoftheOswaldAveryAwardfromtheInfectiousDiseasesSocietyofAmerica.Dr.DonnenbergisanactiveInfectiousDiseasescliniciananddirectstheMedicalScientist(MD/PhD)ProgramattheUniversityofMaryland.HeisalsoactiveinmedicaleducationandwasaninauguralmemberofthePassandSuselAcademyofAcademicExcellenceattheUniversityofMaryland.

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