内容简介
Thisbookdescribesapproachesforrecognizingandclassifyingproteinsintofamiliesofevolutionaryrelatedproteins.Reviewingallthemajorresourcesforclassifyingproteinfamilies,thebookcombinesdescriptionsofgeneralphilosophiesofproteinfamilyclassificationsystemswithdetaileddescriptionsandexamplesofselectedfamiliesfoundindifferentbiologicalsystems.Scientistsindiverseareasofbiologyandproteinsciencewilllearnhowtousethevariousresourcesanddatabasesandgainvaluableinsightintohowproteinsevolveandhownewfunctionalrepertoiresemerge.
作者简介
ChristineOrengo,PhD,isProfessorofBioinformaticsatUniversityCollegeLondon.Dr.Orengo'sresearchfocusesonproteinstructurecomparison,classification,andanalysis.HergroupdevelopstheCATHdomainfamilyclassificationandalgorithmsforpredictingproteinfunctionsandfunctionalnetworks.AlexBateman,PhD,isSeniorInvestigatoratWellcomeTrustSangerInstitute,whereheleadsthePfamdatabaseproject.Dr.BatemanalsoparticipatesintheEuropeanInterProproject,whichseekstomergetheannotationsfromPfam,PRINTS,Prosite,andotherdomaindatabases.