内容简介
KeynotespeakersatthecellsignalingmeetinginLuxembourghaveprovidedchaptersonhypoxiasignaltransduction,phosphoserine/threonine-bindingdomains,targetingofpolycombrepressivecomplexes,conservedsignalingmechanismsininnateimmunity,andsignaltransductionbystress-activatedMAPkinases.Othertopicsincludedamongthesereportsonrecentresearcharereceptorsignaling,proteinkinasecascadesastherapeutictargets,celldeathincancer,inflammation-specificsignaling,cellsignalingpathwaysleadingtoregulatedchromatinmodifications,andtranscriptionalcontrol.Thechaptershavebeenpublishedinfourvolumes(PartAtoD),offeringacomprehensiveoverviewaboutthisexcitingtopic.Thisthirdvolumefocusesonthetherapeuticpotentialfortargetingcellsignalingmechanismswithparticularattentiontocellsignalinginhealthysystemsaswellasindisease.Cancertherapiesandtheimportantareaofchemopreventionareincluded.NOTE:Annalsvolumesareavailableforsaleasindividualbooksorasajournal.Forinformationoninstitutionaljournalsubscriptions,pleasevisitwww.blackwellpublishing.com/nyas.ACADEMYMEMBERS:PleasecontacttheNewYorkAcademyofSciencesdirectlytoplaceyourorder(www.nyas.org).MembersoftheNewYorkAcademyofSciencereceivefull-textaccesstotheAnnalsonlineanddiscountsonprintvolumes.Pleasevisithttp://www.nyas.org/MemberCenter/Join.aspxformoreinformationaboutbecomingamember