书目

NickelandItsSurprisingImpactinNature:MetalIonsinLifeSciences

内容简介

HelmutSigel,AstridSigelandRolandK.O.Sigel,inclosecooperationwithJohnWiley&Sons,launchanewSeries“MetalIonsinLifeSciences”.ThephilosophyoftheSeriesisbasedontheonesuccessfullyappliedtoapreviousseriespublishedbyanotherpublisher,butthemovefrom“biologicalsystems”to“lifesciences”willopentheaimsandscopeandallowforthepublicationofbookstouchingontheinterfacebetweenchemistry,biology,pharmacology,biochemistryandmedicine.Volume2focusesonthevibrantresearchareaconcerningnickelaswellasitscomplexesandtheirroleinNature.Withmorethan2,800referencesandover130illustrations,itisanessentialresourceforscientistsworkinginthewiderangefrominorganicbiochemistryallthewaythroughtomedicine.In17stimulatingchapters,writtenby47internationallyrecognizedexperts,NickelandItsSurprisingImpactinNaturehighlightscriticallythebiogeochemistryofnickel,itsroleintheenvironment,inplantsandcyanobacteria,aswellasforthegastricpathogenHelicobacterpylori,forgeneexpressionandcarcinogenensis.Inaddition,itcoversthecomplex–formingpropertiesofnickelwithaminoacids,peptides,phosphates,nucleotides,andnucleicacids.Thevolumealsoprovidessophisticatedinsightsintherecentprogressmadeinunderstandingtheroleofnickelinenzymessuchasureases,hydrogenases,superoxidedismutases,acireductonedioxygenases,acetyl–coenzymeAsynthases,carbonmonoxidedehydrogenases,methyl–coenzymeMreductases...anditrevealsthechaperonesofnickelmetabolism.

作者简介

AstridSigelhasstudiedlanguagesandwasaneditoroftheMetalIonsinBiologicalSystemsseries(untilVolume44)andalsooftheHandbooksonToxicityofInorganicCompounds(1988),onMetalsinClinicalandAnalyticalChemistry(1994;bothwithH.G.Seiler),andonMetalloproteins(2001;withIvanoBertini)(Dekker,NewYork).HelmutSigelisEmeritusProfessor(2003)ofInorganicChemistryattheUniversityofBasel,Switzerland,andapreviouseditoroftheMIBSseriesuntilVolume44.Heservesonvariouseditorialandadvisoryboards,publishedover300articlesonmetalioncomplexesofnucleotides,coenzymes,andotherligandsofbiologicalrelevance,andlecturedworldwide.HewasnamedProtagonistinChemistry(2002)byICA(issue339);amongfurtherhonorsaretheP.RayAward(IndianChemicalSociety,ofwhichheisalsoanHonoraryFellow),theWernerAward(SwissChemicalSociety),aDoctorofSciencehonoriscausadegree(KalyaniUniversity,India),appointmentsasVisitingProfessor(e.g.,Austria,China,UK)andEndowedLectureships.RolandK.O.SigelisAssistantProfessor(2003)ofInorganicChemistryattheUniversityofZürich,Switzerland,endowedwithaF?rderungsprofessuroftheSwissNationalScienceFoundation.Hereceivedhisdoctoraldegreesummacumlaude(1999)fromtheUniversityofDortmund,Germany,workingwithBernhardLippert;thereafterhespentnearlythreeyearsatColumbiaUniversity,NewYork,USA,inthegroupofAnnaMariePyle(nowYaleUniversity);duringthesixyearsabroadhereceivedseveralfellowshipsfromvarioussources.Hisresearchfocusesonthestructuralandcatalyticroleofmetalionsinribozymes,especiallygroupIIintrons,andonrelatedtopics.HewasalsoaneditorofVolumes43and44oftheMIBSseries.

丛书

MetalIonsinLifeSciences

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