内容简介
"Thisbookcontainsextremelydetailedandinformativecontentonstructureandfunctionofligands,receptors,andsignallingintermediatesplusinteractions…theextentofdetailandappropriatereferencingisimpressive."–MicrobiologyToday,July2009"Averywell–writtenbooksuitableforuseasareferenceortextbookforanundergraduatesubjectincellsignalling.Forresearchersinterestedinthemolecularbasisofcellsignallingandhowaberrantregulationofcellsignallingproteinscausesdiseases,thisisanexcellentresourceofbiochemicalandstructuralinformation."–AustralianBiochemist,August2009"Frombasicstodetails,thisisanelegantlywrittenandcarefullyeditedbook.Thechaptersoncellcyclecontrolandoncogenesisareparticularlyfascinatingandvaluabletobiomedicalresearch.Thisisthebooktohaveifyouareinterestedinmolecularmechanismsofsignaltransduction.Itisagreatintroductiontotheliteraturethatwillbewelcomedbystudentsandexpertsalike."–Doody′s,January2009Thistextisaconciseandaccessibleintroductiontothedynamicbutcomplexfieldofsignaltransduction.Ratherthansimplycataloguingallsignallingmoleculesanddelineatingeveryknownpathway,thisbookaimstobreaksignallingdownintocommonelementsandactivities–the‘nutsandbolts’ofcellularinformationexchange.Withanemphasisonclarityofpresentationthroughout,thebookteachesthebasicprinciplesfocusingonamaturecoreofknowledge,providingstudentswithafoundationoflearninginthiscomplexandpotentiallyconfusingsubject.ItalsoaddressestheissueofvariationinthenumberingofkeyaminoacidsaswellasfeaturinginteractionwithRasMolsoftware,andexercisestoaidunderstanding.AnaccessibleintroductiontothecomplexfieldofcellsignallingInteractswithRasMolsoftware–freelydownloadableforviewingstructuresin3DIncludesexercisesandclearinstructionsintheuseofRasMolWellillustratedinfullcolourthroughoutStructureandFunctioninCellSignallingisaninvaluableresourcetostudentsacrossarangeoflifesciencedegreeprogrammesincludingbiochemistry,cellandmolecularbiology,physiology,biomedicineandoncology.Thisbookprovidesaclear,accessibleintroductiontothisrapidlyexpandingfield.