内容简介
Asymmetricsynthesishasbecomeamajoraspectofmodernorganicchemistry.Thestereochemicalpropertiesofanorganiccompoundareoftenessentialtoitsbioactivity,andtheneedforstereochemicallypurepharmaceuticalproductsisakeyexampleoftheimportanceofstereochemicalcontrolinorganicsynthesis.However,achievinghighlevelsofstereoselectivityinthesynthesisofcomplexnaturalproductsrepresentsaconsiderableintellectualandpracticalchallengeforchemists.Writtenfromasyntheticorganicchemistryperspective,thistextprovidesapracticaloverviewofthefield,illustratingawiderangeoftransformationsthatcanbeachieved.Thebookcapturesthelatestadvancesinasymmetriccatalysiswithemphasisplacedonnon-enzymaticmethods.Topicscoveredinclude:Reductionofalkenes,ketonesandiminesNucleophilicadditiontocarbonylcompoundsCatalyticcarbon-carbonbondformingreactionsCatalyticreactionsinvolvingmetalcarbenoidsConjugateadditionreactionsCatalysisinAsymmetricSynthesisbridgesthegapbetweenundergraduateandadvancedleveltextbooksandprovidesaconvenientpointofentrytotheprimaryliteraturefortheexperiencedsyntheticorganicchemist.