书目

CatalysisinAsymmetricSynthesis(PostgraduateChemistrySeries)

内容简介

Asymmetricsynthesishasbecomeamajoraspectofmodernorganicchemistry.Thestereochemicalpropertiesofanorganiccompoundareoftenessentialtoitsbioactivity,andtheneedforstereochemicallypurepharmaceuticalproductsisakeyexampleoftheimportanceofstereochemicalcontrolinorganicsynthesis.However,achievinghighlevelsofstereoselectivityinthesynthesisofcomplexnaturalproductsrepresentsaconsiderableintellectualandpracticalchallengeforchemists.Writtenfromasyntheticorganicchemistryperspective,thistextprovidesapracticaloverviewofthefield,illustratingawiderangeoftransformationsthatcanbeachieved.Thebookcapturesthelatestadvancesinasymmetriccatalysiswithemphasisplacedonnon-enzymaticmethods.Topicscoveredinclude:Reductionofalkenes,ketonesandiminesNucleophilicadditiontocarbonylcompoundsCatalyticcarbon-carbonbondformingreactionsCatalyticreactionsinvolvingmetalcarbenoidsConjugateadditionreactionsCatalysisinAsymmetricSynthesisbridgesthegapbetweenundergraduateandadvancedleveltextbooksandprovidesaconvenientpointofentrytotheprimaryliteraturefortheexperiencedsyntheticorganicchemist.

作者简介

Dr?Vittorio?CaprioLecturer?in?Organic?and?Medicinal?Chemistry?intheDepartmentofChemistry,UniversityofAuckland,NewZealand.Hisresearchinterestslieintheapplicationofsyntheticorganicmethodstothesynthesisofbioactivenaturalproductsofdiversestructure.Acentralaimistheefficientandelegantsynthesesoftargetcorestructuresinastereocontrolledmannerusingnatureasthesourceofchirality.Theultimategoalistousenaturalmedicinesasthebasisfordesigningandsynthesizingdrugsofgreatertherapeuticvalue.?ProfessorJonathanMJWilliams(authorofthefirstedition)

丛书

PostgraduateChemistrySeries

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