ProteinCondensation:KineticPathwaystoCrystallizationandDisease

Thequesttounderstandthecondensationofproteinsfromsolutionsisarapidlyevolvingfield.Thepurposeofthisbookistobringtoaninterdisciplinaryaudiencethestate-of-the-artincurrentresearch.Thefirstpartofthebookdealswithissuesrelatedtotheproductionofhighqualityproteincrystalsfromsolution.Sinceproteinfunctionisdeterminedbystructure,highqualityproteincrystalsmustbegrowninordertodeterminetheirstructurebyX-raycrystallography.Thebookalsodiscussesdiseasesthatoccurduetoundesiredproteincondensation,anincreasinglyimportantsubject.Examplesincludesicklecellanemia,cataractsandAlzheimer'sdisease.Currentexperimentalandtheoreticalworkonthesediseasesisdiscussed,whichseeksunderstandingatafundamental,molecularlevel,topreventtheundesiredcondensationfromoccurring.Thebook,containingcolorplatesections,issuitableforgraduatestudentsandacademicresearchersinphysics,chemistry,structuralbiology,proteincrystallographyandmedicine.