MethodsandApplicationsofStatisticsintheLifeandHealthSciences

InspiredbytheEncyclopediaofStatisticalSciences,SecondEdition,thisvolumeoutlinesthestatisticaltoolsforsuccessfullyworkingwithmodernlifeandhealthsciencesresearchDatacollectionholdsanessentialpartindictatingthefutureofhealthsciencesandpublichealth,asthecompilationofstatisticsallowsresearchersandmedicalpractitionerstomonitortrendsinhealthstatus,identifyhealthproblems,andevaluatetheimpactofhealthpoliciesandprograms.MethodsandApplicationsofStatisticsintheLifeandHealthSciencesservesasasingle,one-of-a-kindresourceonthewiderangeofstatisticalmethods,techniques,andapplicationsthatareappliedinmodernlifeandhealthsciencesinresearch.Speciallydesignedtopresentencyclopediccontentinanaccessibleandself-containedformat,thisbookoutlinesthoroughcoverageoftheunderlyingtheoryandstandardapplicationstoresearchinrelateddisciplinessuchasbiology,epidemiology,clinicaltrials,andpublichealth.Uniquelycombiningestablishedliteraturewithcutting-edgeresearch,thisbookcontainsclassicalworksandmorethantwenty-fivenewarticlesandcompletelyrevisedcontributionsfromtheacclaimedEncyclopediaofStatisticalSciences,SecondEdition.Theresultisacompilationofmorethaneightyarticlesthatexploresclassicmethodologyandnewtopics,including:SequentialmethodsinbiomedicalresearchStatisticalmeasuresofhumanqualityoflifeChange-pointmethodsingeneticsSamplesizedeterminationforclinicaltrialsMixed-effectsregressionmodelsforpredictingpre-clinicaldiseaseProbabilisticandstatisticalmodelsforconceptionStatisticalmethodsareexploredandappliedtopopulationgrowth,diseasedetectionandtreatment,geneticandgenomicresearch,drugdevelopment,clinicaltrials,screeningandprevention,andtheassessmentofrehabilitation,recovery,andqualityoflife.Thesetopicsareexploredincontributionswrittenbymorethan100leadingacademics,researchers,andpractitionerswhoutilizevariousstatisticalpractices,suchaselectionbias,survivalanalysis,missingdatatechniques,andclusteranalysisforhandlingthewidearrayofmodernissuesinthelifeandhealthsciences.Withitscombinationoftraditionalmethodologyandnewlydevelopedresearch,MethodsandApplicationsofStatisticsintheLifeandHealthScienceshaseverythingstudents,academics,andresearchersinthelifeandhealthsciencesneedtobuildandapplytheirknowledgeofstatisticalmethodsandapplications.