内容简介
ThefirstandonlybookdevotedentirelytoMEMBRANELIPIDASYMMETRYANDITSBIOLOGICALIMPLICATIONSTransmembraneDynamicsofLipidsiscomprisedofcontributionsfromexpertauthorsfromleadingresearchgroupsthatpresentup-to-datequantitativedataontheformation,stability,andbiologicalconsequencesoftheasymmetricalorganizationoflipidsincellmembranes.Incorporatinganimpressiveamountofnew,previouslyuncollecteddata,thebookexaminestransmembraneasymmetryandmovementoflipidsinbiologicalmembranes,andmethodsforthemeasurementoftransmembranelipidmotion,emphasizingtheroleoflipidflippasesanddiscussesbiologicalfunctionsassociatedwithlipidasymmetry.Inaddition,itdrawsattentiontoimportantnewdiscoveriesinthefield,suchasthecorrelationbetweenmalfunctionoflipidflippasesandhumandiseasessuchasthrombosisandcancer.Thebookalsoaddressesthemanifoldmethodsthatareusedtomeasuretherateoftransmembranemovementoflipidsinbiologicalandmodelsystems.Theonlyguidetonewdiscoveriesregardinglipidsincellmembranes,TransmembraneDynamicsofLipidsisdesignedtoappealtobiophysicists,biochemists,andcellularandmolecularbiologistsworkinginthegrowingfieldofmembraneresearch.
作者简介
PhilippeF.Devaux,PhD,isProfessorofPhysicsattheParis7University.Hehaslong-standingexpertiseinteachingmolecularandcellularbiophysicsandphysicsappliedtobiologyandmedicine.Heistheauthorofalmosttwohundredscientificpapersandthreebooks,andisanEditoroftheEuropeanBiophysicsJournal.AndreasHerrmann,PhD,isProfessorofMolecularBiophysicsatHumboldt-UniversityofBerlin.Heteachescoursesonthesubjectsofmolecular;cell;andmembranebiophysics,opticalspectroscopy,andfluorescencemicroscopy.Heistheauthorofmorethantwohundredscientificpapersfocusingonlipiddynamicsinbiologicalmembranesandmolecularmechanismsofvirusinfection.