内容简介
KinaseInhibitorDrugscoversawideandcomprehensiverangeoftopicsaboutkinase–targetedinhibitorsincancertherapy,oneofthehottestdrugtargetsinmoderndrugdiscovery.Itbringstogetherandsummarizesimportantinformationandadvancesinthefieldtoallowresearchersanddrugdiscovererstoeasilydiscernthestateoftargetedcancerdrugdiscovery.Completewithcasestudiesofapprovedkinaseinhibitorsorthoseinlate–phaseclinicaltrialsforcancertherapy,thisisanidealreferenceforpharmaceuticalscientistsdevelopingsmallmoleculeandbiotechdrugstotreatcancer.
作者简介
RongshiLi,PhD,isanAssociateProfessorintheDrugDiscoveryDepartmentatH.LeeMoffittCancerCenterandResearchInstituteinTampa,Florida.JeffreyA.Stafford,PhD,hasleddrugdiscoveryresearchatGlaxoSmithKline,Syrrx,andTakeda.Heisaco-inventorofthetyrosinekinaseinhibitor,pazopanib(Armala).